How Do Alcohol and Other Drugs Impact Your Mind and Body?

While your college experience probably won’t look like a scene out of Animal House, the truth of the matter is that it’s a time when some kids will experiment with drugs and alcohol. Whether you plan to partake or not, it’s best to go in understanding the effects of mind-altering substances.

General info

  • Most drugs produce an initial high, then a crash.

  • When you consume a drug that mimics brain chemicals, your brain responds by producing LESS of those chemicals to try to maintain homeostasis, or a natural balance.

  • When the drug wears off, you wind up with less of the chemicals than you need, which can lead you to crave more of the drug to return to an artificial level. And so begins the cycle of addiction.

  • Consuming drugs and alcohol can reduce inhibitions and result in actions or behaviors that you will later regret — or even worse, are unsafe.

  • Thanks to social media, anything you do can end up shared far and wide. Don’t let one night of recklessness negatively impact your future.

Alcohol

  • Alcohol is a depressant, which means it slows down brain function so there may be less worry, but also less ability to think things through.

  • It can produce intense emotions including euphoria or rage.

  • Extended use increases symptoms of depression and anxiety.

  • Alcohol COUNTERACTS the effects of most antidepressant medications, and has potentially dangerous interactions with others.

  • Do not mix alcohol and monoamine oxidase inhibitors (MAOIs) like socarboxazid (Marplan), phenelzine (Nardil), or selegiline (Emsam) because it can cause dangerous spikes in blood pressure.

  • Do not mix alcohol and prescription anti-anxiety drugs — benzodiazepines like Xanax or Klonopin — or prescription painkillers. They all suppress lung function, and the combination can be fatal!

  • If you’ve heard about celebrities who have died from an overdose, very often they were mixing depressants.

Stimulants

  • Stimulants include methamphetamine, cocaine, misused ADHD meds, and even nicotine or large quantities of caffeine.

  • They speed up brain function, which can increase focus and motivation, but can also cause jitteriness, increased anxiety, paranoia, and heart palpitations.

  • Large quantities can lead to temporary psychosis or — in some cases — full-on psychotic breaks.

  • Nicotine — the chemical compound that makes cigarettes highly addictive — produces an initial rush, then a crash which can only be fixed with — you guessed it — more nicotine.

  • NOTE: Mixing stimulants and depressants — called speedballing — or combining two or more from one category, greatly increases their risks!

Marijuana

  • Marijuana goes by many names, including pot, weed, hash, ganga, grass, reefer, bud, cannabis, chronic, and many, many more.

  • It can function as a depressant, stimulant, hallucinogen, or any combination.

  • It often produces a high, including euphoria; some people report painkilling properties.

  • Marijuana can increase social anxiety, produce full-on paranoia, or lead to panic attacks.

  • It can also trigger psychotic episodes, especially when mixed with ADHD medications or other stimulants.

  • Marijuana interferes with focus and motivation. While you’re high, you feel good despite not solving your problems. Then when you’re not high, your brain produces less of the chemicals it uses to motivate you.

Hallucinogens

  • Hallucinogens — also called psychedelics — include psilocybin mushrooms (shrooms), LSD (acid), DMT, PCP (angel dust), and MDMA (ecstasy).

  • Some psychedelics cause hallucinations, and they tend to affect all the senses – often intensifying them.

  • These hallucinations and sensations can feel very good in the moment — or very, very bad.

  • Hallucinogens have plenty of side effects, but are less likely to cause addiction than anything else on this list.

  • If you have a family history of psychosis, BEWARE. Psychedelics can trigger psychotic episodes.

  • Their effects are EXTREMELY dependent on your mindset and environment. If you are sad, nervous, or in an unfamiliar setting, the likelihood of a “bad trip” is much higher. The only way to end a bad trip is to wait it out.

This article was last reviewed or updated on

This article was last updated on

September 19, 2025

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David Friedlander, PsyD
David Friedlander, PsyD

David Friedlander, PsyD, is a psychologist in the Anxiety Disorders Center at the Child Mind Institute. He specializes in providing evidence-based treatments to children, adolescents, and young adults with anxiety disorders (eg., social anxiety and OCD) and co-occurring disorders such as mood disorders, ADHD, and learning disorders. Dr. Friedlander has received specialized training in cognitive behavioral therapy (CBT), motivational interviewing (MI), dialectical behavior therapy (DBT), supportive parenting for anxious childhood emotions (SPACE), and parent child interaction training for selective mutism (PCIT-SM).

Dr. Friedlander has extensive experience in community mental health outpatient and school settings. He has worked with parents, teachers and other community supports to design behavior plans for use in the home and at school. These evidence-based plans frequently emphasized skill development and involved cognitive, behavioral and mindfulness-based strategies. During quarantine, Dr. Friedlander led weekly online mindfulness meditation sessions for members of his community. He has recently developed an interest in, and presented on, the intersection of technology use (particularly gaming) and mental health. His previous research focused primarily on the mental health needs of ethnic minorities, and he co-authored a chapter in the American Psychiatric Association’s Black Mental Health.

Dr. Friedlander strives to help people experience greater mindfulness and self-compassion in their daily endeavors. He is dedicated to enhancing the lives of children and families by providing them with empathic, evidenced-based care in pursuit of their treatment goals.

Adam Zamora, PsyD

Adam Zamora, PsyD, is the Senior Director of the ADHD & Behavior Disorders Center, Director of the College Success Program, and a neuropsychologist in the Gund Learning and Diagnostic Center at the Child Mind Institute. He specializes in the evaluation and remediation of children, adolescents and young adults with a wide range of conditions that impact academic functioning, including ADHD, verbal and nonverbal learning difficulties, social and interpersonal weaknesses, and emotional disorders. Dr. Zamora utilizes diagnostic interviewing and comprehensive assessments to help provide families with a thorough understanding of their children, to identify assets and strengths, and to unravel the underlying reasons for challenges in their everyday lives. He also takes on an active, collaborative role with families, treatment providers and school personnel to tailor recommendations that help each child meet his or her potential.

In addition to completing his neuropsychological training in academic medical settings, Dr. Zamora has provided psychotherapeutic treatment for children and adolescents with anxiety, mood disorders, behavioral difficulties, trauma histories and complex medical issues in both inpatient and outpatient hospitals and clinics. In a school setting, he has experience with developing behavior plans, conducting social skills groups and helping to facilitate classroom interventions. Dr. Zamora enjoys providing psychoeducation to families and presenting about learning difficulties at local schools. He has also supervised psychology trainees in administration, case conceptualization and report-writing of neuropsychological evaluations.

Dr. Zamora grew up in New York City and has extensive educational consulting experience in the local private school world. Since 2005, he has provided academic consultation and remediation services for students struggling with motivation, study skills, academic performance, test preparation and the school application process. Additionally, as part of his clinical training, Dr. Zamora has conducted numerous school visits and classroom observations, consulted closely with teachers and learning specialists, and advocated for families at IEP meetings and impartial hearings. Dr. Zamora’s work as a clinical psychologist and educational consultant has given him a unique perspective on students and their individual needs, and has aided his ability to translate evaluation results into meaningful clinical summaries with practical, applicable recommendations for use at home and in school. He has a passion for understanding and tapping into individual strengths, and then utilizing those assets to support families and help children overcome areas of weakness.

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You Are Okay is an initiative of the Child Mind Institute, an independent, national nonprofit dedicated to transforming the lives of children and families struggling with mental health and learning disorders.

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Child Mind Institute Logo

You Are Okay is an initiative of the Child Mind Institute, an independent, national nonprofit dedicated to transforming the lives of children and families struggling with mental health and learning disorders.

childmind.org

© 2024 Child Mind Institute. All rights reserved.

Child Mind Institute Logo

You Are Okay is an initiative of the Child Mind Institute, an independent, national nonprofit dedicated to transforming the lives of children and families struggling with mental health and learning disorders. childmind.org

© 2024 Child Mind Institute. All rights reserved.